Kidney transplantation is a good option for people with kidney disease, but there is still
a lot to learn about how to best care for
the HIV infected kidney transplant patient
.
 
Welcome to the HIVTR-CCR5 Project
 
The primary clinical goals of this multi-center clinical trial on HIV+ kidney transplant recipients are as follows:

To evaluate the impact of CCR5 blockade (maraviroc, MVC) on renal function at week 52 post-transplant; as well as evaluate the overall safety and tolerability of CCR5 blockade in the HIV+ kidney transplant recipient.

The primary mechanistic goals of this trial are as follows:

To define immunologic parameters associated with rejection in the HIV positive recipient (versus HIV+ non-rejectors; as well as determine the impact of CCR5 blockade on the immunologic profiles in the HIV positive recipient.

 
NIAID Funding Mechanism: U01AI118594
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